Alzheimer Cure ?

http://neuroprotectivelifestyle.com/inflammation-overload/save-your-heart–save-your-head-in-five-easy-steps/

The only known genetic risk factor for Alzheimer’s disease not surprisingly, is a gene that codes for Apolipoprotein E4. Apolipoprotein E in one of its three isoforms, is responsible for the transport of triglyceride, phospholipid, cholesteryl esters, and cholesterol into cells.

Of the three main isoforms of the apo E allele, apoE3 is most common, followed by apoE4 and lastly apoE2. The lifetime risk for Alzheimer’s disease in someone with apoE3 is about 9%. The lifetime risk for Alzheimer’s in someone with the apoE4 allele is a whopping 29%. If you happen to be homozygous for apoE4 (both alleles on paired chromosomes are apoE4) the lifetime risk for Alzheimer’s sky-rockets to 91% by age 80. Apparently the apoE4 allele is so inefficient at cholesterol metabolism within the brain that sulphated galactocerebroside (sulphatide) levels drop. Sulfatide has everything to do with neuronal plasticity, cell growth and repair in addition to normal signal transduction.

How do you know if you possess the apoE4 allele? While various labs offer this test Berkley Heart Labis consistently the most reliable.

In addition, the one-time Apo E test will help decide whether or not diet will have an effect on elevated cholesterol levels. If you possess the apoE4 isoform without question diet therapy can have dramatic effect on your LDL-C (bad cholesterol) levels. If you have seen your doctor and were told you had elevated LDL-C and have altered your diet without success, then this test is for you.

Here are the five easy steps I recommend for my patients. In this case, I personally take a double dose of my own medicine.

1. Consider Apolipoprotein E testing (ask your doctor)
2. Adopt the Mediterranean diet
3. Increase Omega-3-FA consumption
4. Decrease Omega-6-FA intake (PUFA in the form of vegetable oil)
5. Dramatically increase your intake of dietary polyphenols† (see list below)

To put it another way, make a concerted effort to bathe your body’s biochemical milieu daily in a rich blend of phytochemicals. This is the essence of the “French Paradox”, that is, while the French consume much more saturated fat than their North American counterparts, they also consume far less omega-6-FA’s and far more polyphenols (in the form of red wine primarily), and have much less heart disease to show for it. It is precisely when science flies in the face of convention that you know you’re “gettin’ warm”. So, in the case of the French, consciously or not, they have 3 out of 5 of the “E”asy steps nailed down.

Next time, “How To Put Polyphenols On Your Plate” or “Pass The Polyphenols Please” or something like that! I know, I know…you can’t wait.

†Food sources rich in polyphenols include onion, apple, green-tea, red wine, red grapes, grape juice, strawberries, raspberries, blueberries, cranberries and walnuts to name a few.

http://neuroprotectivelifestyle.com/molecular-detoxification/eat-your-antioxidantsor-else/

A polyphenol-rich diet is the secret to preventing excess calorie consumption. Reducing oxidative stress by caloric restriction is the key mechanism behind slowing the aging process (at least in animals). Check out “Brain Health And The Seven Human Sirtuins” for a closer look at neurobiology of aging.

Artichokes, apricots
Berries (all of em’)
Chocolate
Dill
Eggplant, elder flowerFlax
Guava, ginger, grapes
Hawthorn, honeydew melon
Java apple
Kiwi
Licorice (the real one)
Mango, milk thistle
Nuts, like almonds
Olive oil, oregano, oranges
Pomegranate, paprika, pumpkin
Rhubarb, rose hips
Sweet potato, sesame seeds
Tea green and otherwise, turmeric
Vanilla (not the synthetic extract)
Wine, watermelon
Xanthin’s (yellow foods – peaches, papaya)
Zucchini